Effect of in vivo dexamethasone treatment on body weight, blood glucose, and plasma insulin at 4 weeks after sham or Px
| Sham saline | Sham-Dex | Px-saline | Px-Dex | |
|---|---|---|---|---|
| n | 3 | 3 | 3 | 3 |
| Body weight (g) | 316 ± 18 | 293 ± 20 | 308 ± 7 | 282 ± 13 |
| Blood glucose (mg/dl) | 103 ± 4 | 109 ± 2 | 168 ± 22* | 327 ± 33**† |
| Plasma insulin (ng/ml) | 1.3 ± 0.1 | 2.3 ± 0.3* | 1.6 ± 0.5 | 1.3 ± 0.5 |
Data are means ± SE. Body weight, blood glucose, and plasma insulin were measured 48 h after initial administration of dexamethasone (0.4 mg/kg, once daily for 2 consecutive days) or saline.
* P < 0.05,
† P < 0.01 vs. saline-treated sham rats;
‡ P < 0.05 vs. saline-treated Px rats. Dex, dexamethasone.