TABLE 2

Half-times (t1/2) to steady-state insulin analog NN304 concentrations in plasma and ISF during continuous infusion of analog (3.6 pmol · min−1 · kg−1; group 1) or human insulin + analog (60 + 3.6 pmol · min−1 · kg−1; group 2), or human insulin + analog (120 + 3.6 pmol · min−1 · kg−1; group 3)

Group 1 (analog)Group 2 (human insulin + analog)Group 3 (human insulin + analog)
n864
NN304 half-times (t 1/2)
Plasma t1/2 (min)19 ± 327 ± 328 ± 8
ISF t1/2 (min)91 ± 695 ± 991 ± 8
  • Data are means ± SD.