TABLE 2

Lipolysis data

Responsiveness
Sensitivity
PCOSControlPCOSControl
Basal rate0.6 ± 0.10.4 ± 0.1*
Isoprenaline10.3 ± 1.36.1 ± 1.09.37 ± 0.299.18 ± 0.23*
Dobutamine9.4 ± 1.45.4 ± 1.07.54 ± 0.167.58 ± 0.31*
Terbutaline9.8 ± 1.55.8 ± 1.27.54 ± 0.167.58 ± 0.31*
CGP 121774.2 ± 0.41.7 ± 0.47.57 ± 0.498.42 ± 0.62*
Forskolin9.5 ± 1.25.9 ± 1.26.37 ± 0.166.11 ± 0.16*
dcAMP10.1 ± 1.66.1 ± 1.3§3.92 ± 0.104.93 ± 0.57*
Noradrenaline7.7 ± 1.14.6 ± 1.18.70 ± 0.288.40 ± 0.48*
8bcAMP5.8 ± 0.94.2 ± 1.1
UK 143042.8 ± 0.52.4 ± 0.6*9.41 ± 0.729.51 ± 0.29*
Phenylisopropyl adenosine1.0 ± 0.41.1 ± 0.4*9.47 ± 0.618.14 ± 1.29*
Prostaglandin E22.0 ± 0.31.7 ± 0.6*7.32 ± 0.877.18 ± 0.1*
Insulin2.4 ± 0.52.4 ± 0.7*13.46 ± 0.5114.16 ± 0.27*
  • All values are means ± SE. Responsiveness: glycerol release (μmol · 107 cells−1 · 2h−1) of maximum effective agonist concentration. Sensitivity is negative logarithm of half-maximum effective agonist concentration. Groups were compared using Student’s unpaired two-tailed t test.

  • *

    * Not significant

  • P < 0.05;

  • P < 0.01;

  • §

    § P = 0.056.