TABLE 3

Baseline and steady-state concentrations of intramuscular Pi, ADP, PCr, and pH determined noninvasively using [31P] NMR spectroscopy during AA and saline infusion

Baseline150–180 min270–300 min
Pi (mmol/l)
 AA2.92 ± 0.093.12 ± 0.122.99 ± 0.08
 Control3.16 ± 0.083.62 ± 0.27*3.15 ± 0.18
ADP (μmol/l)
 AA58 ± 257 ± 259 ± 1
 Control60 ± 257 ± 457 ± 3
PCr (mmol/l)
 AA19.50 ± 0.3319.19 ± 0.5919.06 ± 0.53
 Control18.95 ± 0.4119.59 ± 0.5719.22 ± 0.68
pH
 AA7.063 ± 0.0077.037 ± 0.0127.048 ± 0.009
 Control7.052 ± 0.0087.050 ± 0.0207.035 ± 0.008
  • Data are means ± SEM of results from six healthy subjects who underwent both somatostatin insulin glucagon growth hormone clamp tests.

  • *

    * P < 0.05 vs. baseline value, vs. value between 270 and 300 min, and vs. AA.