TABLE 2

Comparison of genotypic and allelic distribution of SNPs between type 2 diabetic and nondiabetic subjects

PolymorphismsGenotypes [n (%)]
PAlleles [n (%)]
P
−11414A/AA/GG/G0.37AG0.59
    T2DM219 (57.0)143 (37.2)22 (5.7)581 (75.7)187 (24.3)
    NDM275 (57.3)187 (40.0)18 (3.7)737 (76.8)223 (23.2)
−11379G/GG/AA/A0.50GA0.51
    T2DM367 (95.6)17 (4.4)0 (0)751 (97.8)17 (2.2)
    NDM454 (94.5)26 (5.5)0 (0)934 (97.3)26 (2.7)
−11365C/CC/GG/G0.25CG0.10
    T2DM233 (60.7)127 (33.1)24 (6.2)592 (77.3)174 (22.7)
    NDM265 (55.2)178 (37.1)37 (7.7)706 (73.8)250 (26.1)
−4034A/AA/CC/C0.19AC0.21
    T2DM327 (85.2)56 (14.6)1 (0.2)710 (92.4)58 (7.6)
    NDM425 (88.5)52 (10.8)3 (0.7)902 (94.0)58 (6.0)
−3964A/AA/GG/G0.03AG0.49
    T2DM334 (87.0)50 (13.0)0 (0)718 (93.5)50 (6.5)
    NDM429 (86.4)47 (9.8)4 (0.8)905 (94.3)55 (5.7)
45T/TT/GG/G0.01TG0.003
    T2DM164 (42.7)169 (44.0)51 (13.3)497 (64.7)271 (35.3)
    NDM251 (52.3)183 (38.1)46 (9.6)685 (71.4)275 (28.6)
276G/GG/TT/T0.007GT0.002
    T2DM224 (58.3)142 (37.0)18 (4.7)590 (76.8)178 (23.2)
    NDM236 (49.2)203 (42.3)41 (8.5)675 (70.3)285 (29.7)
349A/AA/GG/G0.39AG0.25
    T2DM172 (44.8)169 (44.0)43 (11.2)513 (66.8)255 (33.2)
    NDM237 (49.4)192 (40.0)51 (10.6)666 (69.4)294 (30.6)
712A/AA/GG/G0.42AG0.98
    T2DM126 (32.8)206 (53.7)52 (13.5)458 (59.6)310 (40.4)
    NDM168 (35.0)237 (49.4)75 (15.6)573 (59.7)387 (40.3)
2019D/DD/II/I0.69DI0.41
    T2DM138 (35.9)186 (48.4)60 (15.7)462 (60.2)306 (39.8)
    NDM182 (37.9)232 (48.3)66 (13.8)596 (62.1)364 (37.9)
  • Numbers indicate the location of the SNP relative to the A of the ATG of the initiator Met of the adiponectin gene. D, deletion of nucleotide A at position 2019; I, insertion of nucleotide A at position 2019; NDM, nondiabetic subjects; T2DM, type 2 diabetic subjects. df = 2 and 1 for the distribution of genotypes and alleles, respectively.