TABLE 2

Characteristics of GK and Wistar rats after 6 weeks of high-fat diet or regular diet

Wistar
GK
RDHFDRDHFD
Food intake (g/day)23.6 ± 0.5 (8)23.2 ± 0.6 (8)21.2 ± 0.1 (8)16.8 ± 0.8 (8)*
Body weight (g)407 ± 10 (10)443 ± 14 (10)*287 ± 9 (10)300 ± 9 (12)
Epididymal fat (g)5.3 ± 0.4 (6)12.6 ± 0.8 (6)*3.2 ± 0.2 (8)6.7 ± 0.2 (8)*
Plasma TGs (mg/dl)104 ± 15 (6)196 ± 22 (5)*50 ± 7 (8)154 ± 24 (8)*
Plasma FAs (mmol/l)0.07 ± 0.01 (6)0.14 ± 0.01 (6)*0.08 ± 0.02 (8)0.14 ± 0.02 (8)*
Fasting plasma glucose (mg/dl)118 ± 3 (10)133 ± 8 (10)189 ± 9 (12)201 ± 10 (12)
Fed plasma insulin (mU/ml)118 ± 3 (19)127.2 ± 16.7 (22)*76.1 ± 5.1 (28)88.7 ± 7.3 (22)
  • Data are means ± SE (n replicate measurements in each group). HFD, high-fat diet; RD, regular diet.

  • *

    * P < 0.05 GK vs. Wistar within diet treatment;

  • P < 0.05 HFD vs. RD within animal species.