TABLE 1

Main demographic and biochemical characteristics of the study population

GlibenclamideInsulin
Sex (M/F)14/514/5
Age (years)61 ± 761 ± 7
BMI (kg/m2)29.3 ± 3.429.4 ± 3.5
Weight/height0.94 ± 0.050.94 ± 0.05
Fasting plasma glucose (mg/dl)234 ± 67212 ± 75
Fasting plasma insulin (μU/ml)16.9 ± 1324.6 ± 19
C-peptide (ng/ml)2.8 ± 2.02.1 ± 2.6
HbA1c (%)9.5 ± 1.39.9 ± 1.5
Free fatty acids (μmol/l)799.7 ± 348617.2 ± 366
Total cholesterol (mg/dl)252 ± 33250 ± 38
HDL cholesterol (mg/dl)44 ± 1147 ± 11
LDL cholesterol (mg/dl)168 ± 30172 ± 33
Fibrinogen (mg/dl)291 ± 75316 ± 80
Blood lactate (mmol/l)1.279 ± 0.5821.224 ± 0.558
Blood pyruvate (mmol/l)0.081 ± 0.0280.073 ± 0.029
Blood 3-BOH (mmol/l)0.101 ± 0.1070.092 ± 0.179
Blood AcAc (mmo/l)0.083 ± 0.0600.086 ± 0.092
  • Data are mans ± SD. None of the differences between groups are statistically significant.