TABLE 2

Clinical characteristics of study subjects

Obese subjectsDiabetic subjectsLean subjectsP
n198207186
Age (years)45.5 ± 14.461.3 ± 11.058.2 ± 12.2<0.01*
Sex (M/F)52/14686/12188/98<0.01*
BMI (kg/m2)37.1 ± 7.429.5 ± 4.524.4 ± 2.6<0.0001*
Blood glucose (mmol/l)5.07 ± 1.18.6 ± 2.74.1 ± 1.0<0.0001*
Fasting plasma insulin (pmol/l)164.2 ± 113.152.6 ± 33.0<0.0001*
HOMAir5.3 ± 3.71.39 ± 1.1<0.0001*
Total cholesterol (mmol/l)5.46 ± 1.25.53 ± 1.15.66 ± 1.2NS
Total triglycerides (mmol/l)1.45 ± 1.12.03 ± 1.61.63 ± 1.0<0.001*
HDL cholesterol (mmol/l)1.29 ± 0.31.04 ± 0.31.37 ± 0.4<0.001
  • Data are given as means ± SD.

  • *

    * Obese subjects vs. control subjects;

  • obese subjects vs. diabetic subjects;

  • diabetics subjects vs. control subjects. The statistical analysis of total triglycerides and plasma insulin were performed on log-transformed values, but the untransformed values are given in table. Continuous variables were compared by t test and categorical variables by χ2 test. HOMAIR was not measured in diabetic subjects.