TABLE 2

Baseline and follow-up of clinical and biochemical variables in the study subjects

VariableGroup 1
Group 2
Baseline4 months12 months (n = 8)PBaseline4 months12 months (n = 10)P
BMI (kg/m2)28.7 ± 2.329.1 ± 2.729.6 ± 2NS30.5 ± 3.230.2 ± 3.730.8 ± 3.2NS
Systolic blood pressure (mmHg)135.1 ± 23.9133.3 ± 22.6132 ± 20NS137.3 ± 17.5140 ± 15.3135.6 ± 11.2NS
Diastolic blood pressure (mmHg)82 ± 15.983.6 ± 1271.2 ± 12NS82.1 ± 7.584.6 ± 785 ± 10.6NS
Hb (g/dl)14.72 ± 1.114.12 ± 1.2*14.3 ± 0.80.03814.8 ± 1.115.1 ± 0.814.9 ± 1.1NS
Hematocrit (%)43 ± 3.342.6 ± 1.743 ± 2.8NS43.4 ± 2.744.3 ± 2.743.8 ± 3.6NS
Ferritin (ng/ml)460 ± 109232 ± 110*222 ± 104*<0.0001566 ± 369507 ± 438346 ± 2000.048
Transferrin saturation index (%)33.9 ± 11.319.89 ± 6.1*31 ± 7.4<0.00133.4 ± 931 ± 12.533.9 ± 14.6NS
C-reactive protein (mg/dl)0.50 ± 0.60.57 ± 0.50.31 ± 0.25NS0.3 ± 0.20.7 ± 1.30.31 ± 0.25NS
Fasting glucose (mg/dl)168 ± 44161 ± 31158 ± 20NS154 ± 38165 ± 45151 ± 49NS
Fasting C-peptide (ng/ml)2.86 ± 1.12.76 ± 1.43.05 ± 1.1NS2.38 ± 12.65 ± 1.42.8 ± 1.4NS
Cholesterol (mg/dl)185 ± 33182 ± 30192 ± 32NS194 ± 36195 ± 40184 ± 31NS
LDL cholesterol (mg/dl)99 ± 44109 ± 24107 ± 43NS106 ± 43117 ± 3291.3 ± 34NS
Triglycerides (mg/dl)181 ± 67194 ± 70184 ± 72NS159 ± 84156 ± 87141 ± 33NS
  • *

    * Significantly different from baseline;

  • significantly different from the same parameter at 4 months.