TABLE 1

Clinical and biochemical characteristics of study groups

Nonobese adolescentsObese adolescents
n (M/F)5/311/3
Age (years)14 ± 0.6 (12–16)13 ± 0.6 (10–16)
Ethnicity (white/African-American)6/29/5
Height (cm)167 ± 3 (159–178)162 ± 2 (150–168)
Weight (kg)60 ± 4 (45–76)93 ± 4 (66–113)
BMI (kg/m2)21 ± 0.8 (18–25)35 ± 1.5 (25–44)
% Fat mass18 ± 1.6 (12–24)41 ± 1.6 (28–52)
Fat-free mass (kg)45 ± 3 (34–37)50 ± 2 (38–68)
Fasting glucose (mmol/l)4.8 ± 0.11 (4–5)5.04 ± 0.22 (4.2–5.5)
Fasting insulin (pmol/l)66 ± 9 (30–108)180 ± 12 (66–480)
Insulin-to-glucose ratio0.11 ± 0.01 (0.06–0.14)0.32 ± 0.04 (0.11–0.98)
Fasting C-peptide (pmol/ml)0.40 ± 0.10 (0.20–0.70)0.72 ± 0.09* (0.50–1.50)
Fasting triglyceride (mmol/l)8 ± 2 (4–19)18 ± 4 (4–60)
Fasting FAs (μmol/l)415 ± 55 (256–640)517 ± 50 (258–823)
  • Data are means ± SE (range) unless otherwise indicated.

  • *

    * P < 0.05;

  • P < 0.001.