TABLE 4

Logistic regression analysis with incident type 2 diabetes as the dependent variable stratified by BMI [below (lean) and above (obese) the median = 27.4 kg/m2]

CovariatesLean
Obese
OR (95% Cl)P valueOR (95% Cl)P value
Log CRP
 A. Demographic1.47 (1.06–2.05)0.0211.10 (0.86–1.41)0.5
 B. Demographic + fasting insulin1.46 (1.05–2.05)0.0271.04 (0.81–1.34)0.8
 C. Demographic + SI1.25 (0.88–1.79)0.220.93 (0.70–1.22)0.6
Log PAI-1
 A. Demographic2.02 (1.39–2.93)0.00021.67 (1.27–2.20)0.0003
 B. Demographic + fasting insulin1.89 (1.30–2.75)0.00091.56 (1.18–2.08)0.0022
 C. Demographic + SI1.72 (1.17–2.54)0.00631.48 (1.10–2.00)0.0098
Fibrinogen
 A. Demographic1.32 (0.94–1.85)0.111.00 (0.80–1.26)0.9
 B. Demographic + fasting insulin1.34 (0.96–1.88)0.090.98 (0.78–1.24)0.9
 C. Demographic + SI1.12 (0.78–1.59)0.50.89 (0.70–1.14)0.9
  • *

    * Demographic model includes as covariates age, sex, clinical center, and smoking.