Logistic regression analysis with incident type 2 diabetes as the dependent variable stratified by BMI [below (lean) and above (obese) the median = 27.4 kg/m2]
| Covariates | Lean | Obese | ||
|---|---|---|---|---|
| OR (95% Cl) | P value | OR (95% Cl) | P value | |
| Log CRP | ||||
| A. Demographic | 1.47 (1.06–2.05) | 0.021 | 1.10 (0.86–1.41) | 0.5 |
| B. Demographic + fasting insulin | 1.46 (1.05–2.05) | 0.027 | 1.04 (0.81–1.34) | 0.8 |
| C. Demographic + SI | 1.25 (0.88–1.79) | 0.22 | 0.93 (0.70–1.22) | 0.6 |
| Log PAI-1 | ||||
| A. Demographic | 2.02 (1.39–2.93) | 0.0002 | 1.67 (1.27–2.20) | 0.0003 |
| B. Demographic + fasting insulin | 1.89 (1.30–2.75) | 0.0009 | 1.56 (1.18–2.08) | 0.0022 |
| C. Demographic + SI | 1.72 (1.17–2.54) | 0.0063 | 1.48 (1.10–2.00) | 0.0098 |
| Fibrinogen | ||||
| A. Demographic | 1.32 (0.94–1.85) | 0.11 | 1.00 (0.80–1.26) | 0.9 |
| B. Demographic + fasting insulin | 1.34 (0.96–1.88) | 0.09 | 0.98 (0.78–1.24) | 0.9 |
| C. Demographic + SI | 1.12 (0.78–1.59) | 0.5 | 0.89 (0.70–1.14) | 0.9 |
* Demographic model includes as covariates age, sex, clinical center, and smoking.