TABLE 2

Associations between conventional risk factors at baseline and mortality during a 10-year follow-up in 328 patients with type 2 diabetes

Model 1Model 2
Smoking habits1.11 (0.71–1.72)
BMI1.46 (0.92–2.32)1.53 (0.95–2.48)
2.36 (1.42–3.91)*1.98 (1.17–3.37)
Systolic blood pressure2.15 (1.21–3.80)*2.10 (1.23–3.95)*
2.84 (1.63–4.95)*3.51 (1.96–6.31)*
Diastolic blood pressure0.91 (0.55–1.51)
1.79 (1.13–2.82)
Serum total cholesterol1.04 (0.63–1.73)0.92 (0.55–1.54)
2.21 (1.39–3.54)*1.55 (0.95–2.53)
Serum HDL cholesterol1.38 (0.88–2.17)
0.76 (0.47–1.24)
Serum triglycerides1.41 (0.87–2.29)
1.91 (1.20–3.05)*
HbA1c1.31 (0.78–2.19)1.29 (0.76–2.19)
2.39 (1.47–3.87)*2.02 (1.22–3.35)*
Serum creatinine1.10 (0.64–1.90)
1.83 (1.05–3.20)
Prior cardiovascular disease2.89 (1.81–4.62)*3.64 (2.20–6.03)*
  • Model 1: relative risks (95% CI) adjusted for age, sex, and diabetes duration for the second and third tertile of the distribution of the variable under consideration, with the first tertile as the reference category. The cutoff values for the second and third tertile were as follows: BMI, 25.9 and 30.4 kg/m2; systolic blood pressure, 138 and 158 mmHg; diastolic blood pressure, 81 and 90 mmHg; serum total cholesterol, 5.5 and 6.8 mmol/l; serum HDL cholesterol, 0.9 and 1.2 mmol/l; serum triglycerides, 1.5 and 2.4 mmol/l; HbA1c, 7.0 and 8.9%; and serum creatinine, 68.0 and 83.1 μmol/l. For smoking habits, the table shows the relative risks associated with ever-smoking versus never having smoked. Model 2: relative risks (95% CI) after backward selection of all risk factors shown in the table, adjusted for age, sex, and diabetes duration.

  • *

    * P < 0.01;

  • P < 0.05.