TABLE 2

Effect of IL-10 production on lipids, lipoproteins, and glucose levels

IL-10 production
P
Low (n = 184)Intermediate (n = 185)High (n = 184)
IL-10 pg/ml377 (358–396)763 (746–780)1402 (1331–1474)
BMI (kg/m2)27.2 (26.4–27.9)27.6 (26.8–28.4)27.0 (26.3–27.6)0.7
Total cholesterol (mmol/l)5.95 (5.77–6.12)5.67 (5.53–5.84)5.55 (5.41–5.71)0.001
LDL-cholesterol (mmol/l)3.86 (3.71–4.02)3.67 (3.53–3.80)3.55 (3.42–3.69)0.002
Triglycerides (mmol/l)1.77 (1.63–1.91)1.61 (1.48–1.74)1.36 (1.28–1.44)<0.001
HDL-cholesterol (mmol/l)1.28 (1.21–1.34)1.29 (1.23–1.34)1.39 (1.33–1.44)0.009
Glucose (mmol/l)7.50 (7.09–7.91)7.08 (6.68–7.48)6.31 (6.00–6.61)<0.001
HbA1c (%)6.01 (5.83–6.19)5.82 (5.65–6.00)5.55 (5.46–5.65)<0.001
  • Data are presented as means (95% CI). Production capacity of IL-10 was assessed in a whole blood stimulation and were grouped into three equal strata. This was done separately for women and men, as women have lower IL-10 production than men.