TABLE 1

Baseline demographic, anthropometric, and metabolic characteristics of nondiabetic participants in the IRAS, according to conversion to type 2 diabetes at 5-year follow-up

Baseline variableNonconvertersConvertersP value*
n758148
Sex (F/M)56.07/43.9360.14/39.860.36
Ethnicity (NHW, black, His)40.50/26.25/33.2537.16/27.70/35.140.75
Glucose tolerance (NGT/IGT)73.35/26.6531.76/68.24<0.0001
Age (years)54.37 ± 8.5356.04 ± 7.780.03
BMI (kg/m2)27.89 ± 5.3031.13 ± 6.34<0.0001
Waist circumference (cm)89.25 ± 12.4195.53 ± 13.06<0.0001
Fasting glucose (mg/dl)96.91 ± 10.30106.63 ± 11.96<0.0001
2-h glucose (mg/dl)119.36 ± 31.51152.77 ± 30.80<0.0001
Fasting insulin (μU/ml)14.36 ± 11.1422.23 ± 25.72<0.0001
Fasting intact PI (pmol/l)5.41 ± 4.729.33 ± 7.01<0.0001
Fasting split PI (pmol/l)7.16 ± 6.8113.68 ± 11.53<0.0001
Insulin sensitivity S1 × 10−4 (min−1 · μU−1 · ml−1)2.37 ± 2.061.26 ± 1.56<0.0001
AIR (pmol · ml−1 · min−1)529.38 ± 506.48275.46 ± 305.46<0.0001
  • Data are % and means ± SD unless otherwise indicated; sample sizes vary slightly as a result of occasional missing values. His, Hispanic; NHW, non-Hispanic white.

  • *

    * P values derived from χ2 or t tests, as appropriate;

  • Test performed on log-transformed variable.