TABLE 1

CD25+/CD4high+ phenotype and detection of tetramer-positive cells in type 1 diabetic patients and at-risk and normal subject

SubjectCD4high+/CD25+CD4+/CD25+*Tetramer stainingType 1 diabetes
7810Yes10.928.7Yes
7929Yes11.525.0Yes
7826Yes10.74.1Yes
7858Yes4.35.0Yes
6212Yes7.48.6At risk
7878Yes8.75.2At risk
5574Yes18.05.4At risk
7657No24.7<1At risk
6827No2.1<1At risk
6899No0.2<1At risk
7877No2.0<1No
7842No0.3<1No
1010No4.7<1No
7029No0.4<1No
3116No1.7<1No
  • Data are %. Number of CD25+/CD4+ cells in total cell population gated on the live lymphocyte cell population in forward and side scatter;

  • number of tetramer-positive cells in total cell population gated on the live lymphocyte cell population in forward and side scatter and on CD25+/CD4high+.