TABLE 2

Whole-body FA metabolism

ControlHigh fat
Plasma FA (mmol/l)
 basal0.36 ± 0.040.28 ± 0.03
 clamp0.11 ± 0.010.08 ± 0.01
 intralipid1.43 ± 0.081.62 ± 0.11*
MCRP (ml · min−1 · 100 g−1)
 basal7.42 ± 0.489.61 ± 1.01*
 clamp10.1 ± 0.611.2 ± 0.6
 intralipid7.81 ± 0.597.74 ± 0.30
RP (μmol · min−1 · 100 g−1)
 basal2.60 ± 0.232.59 ± 0.19
 clamp1.12 ± 0.150.94 ± 0.09
 intralipid10.92 ± 0.5312.42 ± 0.64
  • Data are means ± SE for n = 6–8 animals/group. Average plasma FA concentration, whole-body FA clearance (MCRP), and whole-body FA disposal (RP) are presented for rats studied under basal conditions, during hyperinsulinemic-euglycemic clamp or infusion of intralipid and heparin.

  • *

    * P < 0.05,

  • P < 0.01 compared with control.