TABLE 3

Indices of FA clearance (ml · min−1 · 100 g−1) and fate in the white quadriceps muscle and heart

3H-R-BrP clearance
14C-P clearance into storage
ControlHigh fatControlHigh fat
White quadriceps
 basal1.82 ± 0.173.03 ± 0.47*1.44 ± 0.112.18 ± 0.16*
 clamp4.37 ± 0.345.89 ± 0.482.76 ± 0.363.46 ± 0.29*
 intralipid3.20 ± 0.223.60 ± 0.301.46 ± 0.142.13 ± 0.25*
Heart
 basal100.7 ± 7.9119.6 ± 5.9*12.5 ± 2.721.4 ± 3.0*
 clamp91.4 ± 10.3112.9 ± 5.1*50.5 ± 8.261.8 ± 5.9
 intralipid90.2 ± 3.174.7 ± 5.817.6 ± 3.417.2 ± 2.4
  • Data are means ± SE for rats studied under basal conditions, during hyperinsulinemic-euglycemic clamp or infusion of intralipid and heparin (n = 6–10 animals/group).

  • *

    * P < 0.05,

  • P < 0.01 compared with control.