TABLE 1

Animal characteristics

VariableMale
Female
ControlLipidControlLipid
n9787
Body weight (kg)0.305 ± 0.020.282 ± 0.020.181 ± 0.07∗0.200 ± 0.09*
Plasma glucose concentration (mmol/l)
 Basal8.0 ± 0.238.3 ± 0.437.1 ± 0.496.9 ± 0.39
 Clamp8.4 ± 0.088.49 ± 0.128.21 ± 0.098.24 ± 0.1
Plasma insulin concentration (nmol/l)
 Basal0.09 ± 0.0180.08 ± 0.0120.06 ± 0.010.09 ± 0.02
 Clamp7.48 ± 2.57.2 ± 3.29.3 ± 0.5310.2 ± 0.43
Plasma FFA concentration (mmol/l)
 Basal0.69 ± 0.050.65 ± 0.040.53 ± 0.0520.58 ± 0.082
 Clamp0.17 ± 0.0132.96 ± 0.250.31 ± 0.0372.88 ± 0.22
Intralipid infusion rate (μmol · min−1 · kg−1)00.668 ± 0.0400.948 ± 0.02*
  • Data are means ± SE.

  • *

    * Between-sex difference (male versus female), within experimental protocol, control or lipid

  • difference between basal versus clamp, within sex and infusion protocol

  • difference between infusion protocols (control versus lipid) within sex.