TABLE 2

Lipoprotein subclasses and average particle size by diabetes and sex

Men
Women
NondiabeticDiabeticPNondiabeticDiabeticP
n9110110493
Small VLDL (v1,v2) (nmol/l)47.1 (34–70)46.3 (29–64)0.235.2 (14–49)35.3 (14–54)0.6
Medium VLDL (v3,v4) (nmol/l)18.1 (8–31)9.0 (14–23)0.00310.3 (5–18)3.4 (1.5–12)<0.0001
Large VLDL (v5,v6,chylo) (nmol/l)1.9 (0.4–5)1.1 (0.2–3)0.130.8 (0.1–2)0.6 (0.1–2)0.8
Total VLDL particles (nmol/l)74.6 (52–101)59.7 (42–84)0.00251.8 (31–68)41.8 (18–74)0.14
VLDL size (nm)48.2 (45–55)50.2 (43.5–60.6)0.448.8 (45–53.0)56.9 (48.4–66.6)<0.0001
IDL (nmol/l)0 (0–32)0 (0–43)0.40 (0–14)0 (0–158)0.005
Small LDL (L1) (nmol/l)583 (217–975)569 (276–868)0.4315 (51–537)465 (125–743)0.04
Large LDL (L2,L3) (nmol/l)951 (743–1,320)990 (713–1,258)0.61,101 (842–1,296)928 (647–1,144)0.002
Total LDL + IDL particles (nmol/l)1,669 (1,376–2,005)1,489 (1,270–1,816)0.051,445 (1,225–1,667)1,446 (1,151–1,706)0.7
LDL size (nm)21.0 (20.5–21.3)21.1 (20.7–21.4)0.421.3 (21–21.6)21.0 (20.6–21.4)0.0009
Small HDL (H1,H2) (μmol/l)18.7 (14–23)14.8 (11–20)0.00212.7 (8–17)10.7 (7–14)0.006
Medium HDL (H3) (μmol/l)4.0 (1.4–9)3.9 (2–9)0.846.3 (2–10)5.9 (2–12)0.88
Large HDL (H4,H5) (μmol/l)7.8 (6–12)11.8 (8–15)<0.000112.9 (10–15)13.8 (11–18)0.049
Total HDL particles (μmol/l)33.0 (30–36)32.3 (30–35)0.2531.8 (29–35)31.8 (28–34)0.6
HDL Size (nm)8.8 (8.5–9)9.2 (8.9–9.5)<0.00019.4 (9–9.7)9.7 (9.3–10)0.0001
  • Data are median (interquartile range). P values shown are for the Mann-Whitney U test of the comparison between diabetic and nondiabetic subjects within each sex. Chylo, chylomicron.