TABLE 1

Clinical and metabolic characteristics of the subjects with type 2 diabetes

Pretreatment10 weeks
Age (years)55 ± 1.5
Duration of diabetes (years)3.9 ± 0.7
BMI (kg/m2)28.9 ± 1.428.6 ± 1.3
Weight (kg)93.6 ± 5.391.5 ± 5.3*
Fat-free mass (kg)65.7 ± 365.4 ± 3
HbA1c (%)6.2 ± 0.36.0 ± 0.4
Glucose (mmol/l)8.3 ± 0.57.1 ± 0.4
Insulin (pmol/l)62.4 ± 7.244.4 ± 7.2*
Free fatty acids (mmol/l)0.7 ± 0.10.7 ± 0.1
Cholesterol (mmol/l)5.1 ± 0.44.7 ± 0.2
Triglycerides (mmol/l)2.0 ± 0.41.9 ± 0.3
HDL cholesterol (mmol/l)1.14 ± 0.11.26 ± 0.1
LDL cholesterol (mmol/l)3.1 ± 0.32.7 ± 0.2
Lactate (mmol/l)0.85 ± 0.070.96 ± 0.17
  • Date are means ± SE. n = 8 (7 men, 1 woman). All measurements were done after an overnight fast.

  • *

    * P < 0.001,

  • P < 0.01,

  • P < 0.05 vs. pretreatment.