TABLE 2

AGE content in diets (LAD and HAD) and in mouse sera of db/db and controls on LAD and HAD

Diet AGESerum AGE
Control mice (U/ml)
db/db mice (U/ml)
Baseline14 weeksBaseline14 weeks
n810
LAD209.7 U/mg52 ± 483 ± 6*53 ± 493 ± 14
HAD718.5 U/mg54 ± 3116 ± 857 ± 5194 ± 43
  • Data were obtained by ELISA using 4G9 monoclonal antibody (29,30) and are means ± SE.

  • *

    * P < 0.05 (P calculated for LAD-fed versus HAD-fed control mice;

  • P calculated for LAD-fed versus HAD-fed db/db mice).