TABLE 1

Measures of insulin secretion after the first and final transplant

After first transplantAfter final transplant
IE infused374,283 ± 20,247850,035 ± 37,911
AIRg (% of control)2 ± 121 ± 5
AIRarg (% of control)17 ± 356 ± 11
AUCi (% of control)10 ± 434 ± 5
  • Data are means ± SE based on the 17 subjects (for IE infused) who completed the Edmonton protocol; n = 13 for the glucose studies (both after first and final transplant) and n = 6 after first transplant and n = 8 after final transplant for the arginine studies. Nondiabetic subjects are reported as having 1.0–1.7 × 106 islets (23,24).