TABLE 2

Clinical characteristics of nondiabetic subjects from San Giovanni Rotondo according to carrying status of adiponectin 45-276 haplotype TG

Haplotype 45-276
TG/TGTG/X + X/XP
n106 (27.1)285 (72.9)
M/F44/62109/1760.38
Age (years)39 ± 1237 ± 110.32
% IBW120 ± 22114 ± 190.03
Waist (cm)84.9 ± 1180.6 ± 120.004
Systolic blood pressure (mmHg)116 ± 12112 ± 120.01
Diastolic blood pressure (mmHg)78 ± 975 ± 80.003
Fasting blood glucose (mmol/l)5.1 ± 0.54.9 ± 0.50.02
Serum insulin (pmol/l)53 ± 3242 ± 210.005*
HOMAIR2.01 ± 1.31.56 ± 0.80.003*
Cholesterol (mmol/l)5.15 ± 1.094.99 ± 1.020.11
HDL cholesterol (mmol/l)1.32 ± 0.361.39 ± 0.320.13
Total/HDL ratio4.1 ± 1.33.8 ± 1.10.01
Triglycerides (mmol/l)1.22 ± 0.981.02 ± 0.630.06*
  • Data are means ± SD. X denotes any haplotype other than TG. Significance tests were based on the comparison of three genotype groups (TG/TG vs. TG/X vs. X/X). Because TG/X heterozygotes and X/X homozygotes were virtually identical for every variable, these groups were combined for presentation. Genotypes were available at both positions for 391 study subjects.

  • *

    * Significance was tested on log-transformed values.