TABLE 1

Clinical measurements according to PPAR-γ2 gene polymorphism

Pro12ProPro12Ala/Ala12AlaP
N324152
M/F112/21259/93
Age (years)69.5 ± 2.869.8 ± 2.90.27
BMI (kg/m2)27.5 ± 4.428.0 ± 4.30.30
Glucose 0 min (mmol/l)5.68 ± 1.21*5.47 ± 1.24*0.06
Glucose 120 min (mmol/l)7.94 ± 1.45*7.80 ± 1.43*0.64
Insulin 0 min (pmol/l)71 ± 1.72*61 ± 1.75*0.01
Insulin 120 min (pmol/l)487 ± 1.98*506 ± 1.89*0.58
Proinsulin (pmol/l)3.21 ± 2.06*2.82 ± 2.15*0.07
32-33 split proinsulin (pmol/l)8.14 ± 2.08*7.83 ± 1.97*0.58
HOMA-IR index18.0 ± 1.8314.9 ± 1.800.05
Cholesterol (mmol/l)5.9 ± 1.16.1 ± 1.10.12
HDL cholesterol (mmol/l)1.43 ± 1.32*1.46 ± 1.32*0.41
LDL cholesterol (mmol/l)3.8 ± 0.93.9 ± 1.00.25
Triglycerides (mmol/l)1.29 ± 1.50*1.31 ± 1.57*0.73
  • Data are means ± SD.

  • *

    * Geometric means ± SD. P values were adjusted for age, sex, and adult BMI.