TABLE 1

Body weight, blood glucose, and plasma measurements in 10-week-old KO and WT mice

Wild typeKnockoutP
Body weight (g)17.9 ± 0.8 (11)13.9 ± 0.9 (10)<0.01
Fasting blood glucose (mg/dl)79.8 ± 5.9 (9)98.3 ± 7.7 (10)0.245
Fed blood glucose (mg/dl)120.2 ± 6.4 (11)107.0 ± 10.0 (10)0.272
Fasting insulin (ng/ml)0.177 ± 0.01 (11)0.191 ± 0.01 (10)0.337
Fed insulin (ng/ml)0.213 ± 0.02 (7)0.187 ± 0.02 (8)0.448
Fasting FFAs (mEq/l)0.827 ± 0.06 (11)0.599 ± .03 (11)<0.001
Fasting triglycerides (mg/dl)59.52 ± 1.71 (12)42.31 ± 4.33 (11)<0.001
Fasting leptin (ng/ml)1.33 ± 0.07 (12)1.63 ± 0.46 (12)0.068
  • Data are means ± SE (number of animals). Body weight, glucose, and insulin were measured in male mice; FFAs, triglycerides, and leptin were measured in female mice.