TABLE 2

Body weight parameters, blood glucose, plasma insulin in WT and KO mice fed LF or HF diets

	WTHF	WTLF	KOHF	KOLF	P
	WTHF	WTLF	KOHF	KOLF					Genotype	Diet
n	11	11	11	10
Body weight (g)	28.1 ± 0.9^a	24.3 ± 0.9^b	24.4 ± 1.0^b	22.5 ± 0.9^b	<0.01	<0.005
Weight/length (g/cm)	2.85 ± 0.09^a	2.55 ± 0.07^b	2.5 ± 0.1^b	2.39 ± 0.08^b	<0.01	<0.05
Liver weight (g)	1.07 ± 0.04	1.1 ± 0.04	1.00 ± 0.04	1.07 ± 0.03	NS	NS
Total fat weight (g)	5.8 ± 2.1^a	3.4 ± 1.9^b	3.7 ± 2.1^b	2.62 ± 1.1^b	<0.01	<0.005
Total fat (%)	20.1 ± 0.6^a	13.5 ± 0.6^b	14.4 ± 0.6^b	11.4 ± 0.4^b	<0.01	<0.005
Food intake (kcal)	6,045 ± 180^a	3,505 ± 36^b	5,652 ± 499^a	3,713 ± 229^b	NS	<0.01
Fasting glucose (mg/dl)	93.64 ± 7.1	83.64 ± 7.2	84.91 ± 3.9	80.8 ± 4.8	NS	NS
Fasting insulin (ng/ml)	0.36 ± 0.03^a (n = 8)	0.32 ± 0.01 (n = 9)	0.28 ± 0.01^b (n = 9)	0.30 ± 0.01 (n = 8)	<0.05	NS

Data are means ± SE. Fetuin KO and WT mice (females, 10 weeks old) were fed HF or LF diets ad libitum for 9 weeks and were monitored weekly for food intake. End-of-study body weight parameters and total caloric intake are shown. Values were dissimilar superscript letters (^a or ^b) are significantly different from each other based on genotype or diet.