TABLE 2

Basal and pusatile insulin secretion

Fasting
Control
PREPOSTPREPOST
Total secretion (pmol/l/min)2.9 ± 0.4*11.1 ± 0.95.4 ± 0.912.7 ± 2.3
Frequency (min/pulse)6.3 ± 0.45.1 ± 0.26.1 ± 0.45.4 ± 0.3
Mass (pmol/l/pulse)10.1 ± 1.7*28.5 ± 3.816.0 ± 3.230.9 ± 5.1
Amplitude (pmol/l/min)4.0 ± 0.7*11.4 ± 0.76.4 ± 1.312.5 ± 2.0
Basal secretion (pmol/l/min)1.2 ± 0.3*5.5 ± 0.42.7 ± 0.36.6 ± 1.4
Pulsatile secretion (pmol/l/min)1.6 ± 0.2*5.6 ± 0.92.7 ± 0.66.1 ± 1.2
  • Data are means ± SE. The deconvoluted characteristics of pulsatile insulin secretion is given. PRE, pre–glucose infusion; POST, post–glucose infusion.

  • *

    * P < 0.05 for fasting vs. control

  • P < 0.05 for pre– vs. post–glucose infusion.