TABLE 4

Estimates of allele frequencies for SNPs in known candidate genes for type 2 diabetes

GeneVariantProband pool*SDNormal pool*SDP
KIR6.2Glu23Lys67.1 G/32.9 A1.866.9 G/33.1 A2.11.026
CALPAIN 63nt1637889.6 C/10.4 T1.887.6 C/12.4 T1.50.583
CALPAIN 43nt485267.6 C/32.4 T0.963.8 C/36.2 T1.20.407
CALPAIN 62nt1611240 G/60 A2.539.8 G/60.2 A1.71.025
SUR 18C/T exon 2297.2 C/2.8 T0.798.0 C/2.0 T0.40.816
PPARĪ³ 21Pro12Ala6.6 G/93.4 C17.7 G/92.3 C2.30.770
IRS512Ala512Pro4.4 G/95.6 C0.84.6 G/95.3 C0.61.046
IRS972Gly972Arg80.9 C/19.1 T2.982.6 C/17.4 T2.20.698
  • *

    * Allele frequency (%); n = 300.