TABLE 3

Baseline and 4-year follow-up data and 4-year changes in anthropometric and metabolic values in participants who participated in repeated FSIGT examination

Intervention group
Control group
Baseline*4-yearChangenPBaseline4-yearChangenP
Age (years)56 ± 755 ± 7
Weight (kg)84.6 ± 13.979.6 ± 15.8−4.9 ± 4.9§31<0.00184.9 ± 14.283.5 ± 14.3−1.4 ± 5.521<0.001
BMI (kg/m2)30.4 ± 3.928.6 ± 4.4−1.8 ± 1.931<0.00130.5 ± 4.130.0 ± 3.9−0.5 ± 2.0210.227
Waist circumference (cm)102.3 ± 11.098.1 ± 12.2−4.2 ± 5.2§31<0.001102.0 ± 8.399.9 ± 7.8−1.8 ± 4.5200.096
Fasting glucose (mmol/l)6.2 ± 0.86.3 ± 0.80.08 ± 0.73310.5576.2 ± 0.66.3 ± 0.70.10 ± 0.75210.537
2-h glucose (mmol/l)8.8 ± 1.69.2 ± 2.80.39 ± 3.09310.5448.6 ± 1.58.9 ± 1.50.23 ± 2.38210.659
Fasting insulin (pmol/l)78.0 ± 36.368.9 ± 38.7−15.4 ± 27.0290.001103.1 ± 57.677.7 ± 29.3−25.7 ± 60.3200.086
2-h insulin (pmol/l)577 ± 405441 ± 290−168 ± 417190.152556 ± 332510 ± 276−68 ± 378150.344
HbA1c (%)5.9 ± 0.95.8 ± 0.5−0.11 ± 0.99300.5595.8 ± 0.95.9 ± 0.50.14 ± 0.95200.531
AIR (mU · l−1 · min−1)272 ± 299244 ± 245−27 ± 162310.281336 ± 284270 ± 210−66 ± 107210.011
Si (×10−4 · min−1 · μU−1 · ml−1)2.13 ± 1.372.64 ± 1.440.34 ± 1.46280.2271.91 ± 1.121.94 ± 0.950.16 ± 0.96200.474
Sg ([min]−1 · 102)1.50 ± 0.541.54 ± 0.500.05 ± 0.69290.6831.66 ± 0.461.34 ± 0.43−0.32 ± 0.63200.036
  • Data are mean ± SD.

  • *

    * There were no significant differences in any of the baseline variables between the intervention and control groups.

  • P value within the study group change.

  • P < 0.05 between the study groups.

  • §

    § P = 0.043 for the change in weight and P = 0.025 for the change in waist circumference, adjusted for age and sex, between the study groups when all participants with follow-up data are included (n = 39 for intervention and n = 29 for control group).