TABLE 4

Regression analyses for the changes of the Si, the acute insulin response, the fasting insulin, and the 2-h insulin

Regression coefficientP value
Change in the Si (n = 48)
 Baseline weight0.100.920
 Age0.370.847
 Sex−0.620.982
 Study group*7.460.769
 Weight change (%)−8.10<0.001
 Change in AIR (mU · l−1 · min−1)−0.150.077
Change in the acute insulin response (n = 48)
 Baseline weight0.230.730
 Age−1.070.408
 Sex0.220.990
 Study group*−7.700.659
 Weight change (%)−3.220.083
 Change in Si (×10−4 · min−1 · μU−1 · ml−1)−10.020.254
Change in the fasting insulin (n = 66)
 Baseline weight−0.930.061
 Age−1.570.065
 Sex4.290.731
 Study group*−10.260.388
 Weight change (%)5.01<0.001
Change in the 2-h insulin (n = 47)
 Baseline weight−0.930.221
 Age0.240.853
 Sex−12.980.542
 Study group*−8.010.679
 Weight change (%)3.890.012
  • *

    * Study groups were encoded as 1 = intervention group and 2 = control group.

  • Weight change was calculated as {[weight (kg)4 year − weight (kg)baseline]/[weight (kg)baseline]} × 100.