TABLE 2

Characteristics of db/db and non-db mice mice exposed to H-AGE and L-AGE diets

H-AGE
L-AGE
BaselineEndBaselineEnd
Body weight (g)db/db51 ± 0.753 ± 0.550 ± 0.551 ± 0.6
non-db22.7 ± 0.423.8 ± 0.322 ± 0.423.1 ± 0.4
Blood glucose (mg/dl)db/db358 ± 34424 ± 43293 ± 26373 ± 25
non-db114 ± 7110 ± 6.5117 ± 5106 ± 5
Food intake (g/day)db/db5 ± 16.2 ± 0.55.2 ± 0.46 ± 0.5
non-db4 ± 0.34.3 ± 0.13.9 ± 0.44.1 ± 0.2
sCML (units/ml)db/db69 ± 4.1104 ± 7.2*71 ± 2.165 ± 2.8
non-db53.4 ± 2.564.3 ± 5.5*52.2 ± 2.748.7 ± 2.3
sMG (nmol/ml)db/db1.7 ± 0.12.4 ± 0.1*1.7 ± 0.11.6 ± 0.1
non-db1.4 ± 0.091.8 ± 0.1*1.4 ± 0.061.4 ± 04
Urinary CML excretion (units/min)db/db334 ± 29186 ± 19*278 ± 17285 ± 20
non-db79.2 ± 20.5187.5 ± 62.371 ± 894.6 ± 23
Urinary MG excretion (nmol/min)db/db2.4 ± 0.21.14 ± 0.3*2 ± 0.12.04 ± 0.1
non-db1.9 ± 0.63.2 ± 0.5*1.5 ± 0.21.8 ± 0.3
Urinary albumin/creatinine ratio (μg/mg)db/db1.6 ± 0.13.9 ± 0.31.6 ± 0.21.9 ± 0.2
non-db0.85 ± 0.20.92 ± 0.20.91 ± 0.20.9 ± 0.1
  • Data are expressed as mean ± SE.

  • *

    * P related to statistically significant differences in both diet groups at the end of the study;

  • P related to statistically significant differences in each diet group between baseline and end of the study.