TABLE 1

Studies that have assessed the effects of FFA per se on glucose production (GP), gluconeogenesis (GNG), and glycogenolysis (GGL)

SpeciesChange in FFAChange in plasma glucoseChange in GPChange in GNGChange in GGLRef. no.
Ferrannini 1983HumanIncreaseClamped9
Boden 1991HumanIncreaseIncrease10
Rebrin 1996DogsIncreaseClamped11
Mittelman 2000DogsDecreaseClamped12
Roden 2000HumanIncreaseIncreaseNo changeNo change13
Chu 2002DogsIncreaseNo changeNo change14