TABLE 5

NMR lipoprotein subclass mass and conventional lipid panel measurements in IS, IR, and type 2 diabetic subjects

ISIRDiabetesP values
IR vs. ISDM vs. IS
NMR lipoprotein subclass
 VLDL (mmol/l)
  Total0.76 ± 0.461.07 ± 0.781.24 ± 0.910.03250.0011
  Large0.18 ± 0.240.43 ± 0.570.57 ± 0.630.01130.0001
  Intermediate0.35 ± 0.260.39 ± 0.260.38 ± 0.310.47300.5712
  Small0.23 ± 0.150.25 ± 0.140.29 ± 0.180.54460.0647
 IDL (mmol/l)0.03 ± 0.080.06 ± 0.140.05 ± 0.110.16680.2560
 LDL (mmol/l)
  Total2.86 ± 0.853.20 ± 0.713.38 ± 0.960.04150.0024
  Large1.72 ± 0.951.56 ± 1.041.12 ± 1.220.44570.0058
  Intermediate0.53 ± 0.700.48 ± 0.600.86 ± 0.950.72140.0311
  Small0.61 ± 0.661.11 ± 1.001.34 ± 1.180.00880.0002
 HDL (mmol/l)
  Total1.10 ± 0.341.00 ± 0.330.93 ± 0.340.11270.0119
  Large0.56 ± 0.320.41 ± 0.330.37 ± 0.340.02720.0049
  Intermediate0.20 ± 0.150.22 ± 0.160.15 ± 0.180.60310.1154
  Small0.34 ± 0.150.37 ± 0.130.41 ± 0.150.40030.0173
  Small/large0.94 ± 0.981.71 ± 1.964.38 ± 12.960.60770.0206
Conventional lipid panel
 Total cholesterol (mmol/l)4.33 ± 0.934.71 ± 0.874.99 ± 1.460.08630.0036
 LDL (mmol/l)2.74 ± 0.743.01 ± 0.743.12 ± 1.150.12820.0341
 HDL (mmol/l)1.11 ± 0.311.02 ± 0.301.04 ± 0.410.19870.3390
 Triglycerides (mmol/l)1.07 ± 0.571.49 ± 0.961.88 ± 1.290.0299<0.0001
 Triglycerides/HDL1.03 ± 0.621.72 ± 1.492.18 ± 2.010.01870.0001
  • Data are means ± SD. Boldface data signify statistical significance at P < 0.05. DM, diabetes.