TABLE 2

Chromosomal regions showing evidence for linkage, with a LOD ≥ 1.18 (P ≤ 0.01), to diabetes and related traits using 373 framework STR markers

ChromosomeLocation (cM)TraitPeak LOD scoreEmpirical P valueLOD-1 support interval (cM)Flanking markers
1106Type 2 diabetes1.440.011590–124D1S209, D1S216
104Glucose 1201.630.003190–120D1S209, D1S216
104Glucose 1501.980.001392–120D1S209, D1S216
110Glucose 1802.160.000895–124D1S216, D1S207
236Glucose AUC1.750.002315–45D2S312, D2S220
38Glucose 1201.770.002220–59D2S312, D2S220
150Glucose 1201.590.0034130–170D2S347, D2S368
265HbA1c1.870.0017255–275D2S206, D2S338
440HbA1c1.230.008725–65D4S419, D4S391
139Type 2 diabetes/IGH1.280.0141126–156D4S1575, D4S424
7100Glucose 601.450.004950–120D7S669, D7S657
8160Glucose 1801.270.0078130–165D8S284, D8S272
1411Glucose 01.560.00370–35D14S283, D14S80
14Glucose 1502.810.000160–36D14S283, D14S80
23Glucose 1201.750.002310–40D14S80, D14S70
29Glucose 1802.060.001011–42D14S80, D14S70
33Glucose AUC2.410.000416–53D14S70, D14S288
15114Glucose 1201.300.0072100–120D15S130, D15S1014
16120Glucose 1801.480.0045109–120D16S520
17109Type 2 diabetes/IGH1.480.008190–128D17S949, D17S802
189Glucose 01.500.00430–28D18S59, D18S452
9HbA1c3.070.0000850–31D18S59, D18S452
1945Glucose 1201.370.006030–55D19S226, D19S433