TABLE 2

Glomerular morphometric parameters in the type 2 diabetic patients and control subjects

Control subjectsNAMAPP (ANOVA)
Nv(epi/glom) (n/× 106 μm3)263 ± 110175 ± 72*115 ± 4598 ± 46<0.0001
Epi N/glom833 ± 184654 ± 265592 ± 283554 ± 311<0.002
FSLv/glom (μm/μm3)NA0.27 ± 0.08*0.21 ± 0.070.17 ± 0.07<0.0001
FPW (nm)NA560 ± 88§663 ± 110724 ± 210<0.004
MGV (× 106 μm3)3.5 ± 1.04.1 ± 1.55.2 ± 2.65.4 ± 1.8<0.05
Vv(mes/glom)0.19 ± 0.030.23 ± 0.04§0.25 ± 0.060.34 ± 0.09<0.0001
GBM width (nm)310 ± 38405 ± 49§477 ± 93584 ± 139<0.0001
  • Data are expressed as mean ± 1 SD. NA, not available;

  • *

    * P < 0.01, NA vs. MA and P;

  • P < 0.0001, control vs. all D2;

  • P < 0.01, control vs. MA and P;

  • §

    § P < 0.05, NA vs. MA and P < 0.005, NA vs. P;

  • P < 0.005, MA vs. P.