TABLE 2

Plasma and hepatic parameters after a 4-h fast in lean and ob/ob mice

PlasmaLeanob/ob
 Glucose (mmol/l)8.6 ± 3.016.9 ± 4.6*
 Insulin (ng/ml)1.3 ± 0.96.9 ± 0.6*
 TG (mmol/l)0.3 ± 0.030.7 ± 0.1*
 Cholesterol (mmol/l)1.7 ± 0.44.1 ± 0.3*
 FFA (mmol/l)0.7 ± 0.11.3 ± 0.1*
Liver
 Liver weight (g)1.3 ± 0.12.7 ± 0.3*
 TG (μmol/g liver)1.2 ± 0.42.7 ± 0.5*
 Total cholesterol (μmol/g liver)1.3 ± 0.41.6 ± 0.3*
 Free cholesterol (μmol/g liver)0.8 ± 0.11.0 ± 0.1
 Cholesteryl esters (μmol/g liver)0.1 ± 0.010.5 ± 0.3*
 Phospholipids (μmol/g liver)0.3 ± 0.10.2 ± 0.3
 Glucose-6-phosphate (μmol/g liver)0.2 ± 0.030.1 ± 0.1
 Glycogen (μmol/g liver)212 ± 11183 ± 17
  • Data are means ± SD. n = 5 per group.

  • *

    * P < 0.05, Mann-Whitney U test.