TABLE 4

Neuroglycopenic symptom scores during hyperinsulinemic euglycemic and stepped hypoglycemic clamps in nondiabetic subjects and hyperinsulinemic stepped hypoglycemic clamps in patients with type 1 diabetes

Time (min)Nondiabetic
Diabetic Hypoglycemia
EuglycemiaHypoglycemia
MorningNight awakeNight asleepMorningNight awakeNight asleep
−153 ± 11 ± 01 ± 02 ± 12 ± 11 ± 13 ± 1
03 ± 01 ± 02 ± 12 ± 12 ± 11 ± 12 ± 0
303 ± 11 ± 03 ± 12 ± 11 ± 11 ± 13 ± 0
603 ± 11 ± 04 ± 23 ± 12 ± 12 ± 14 ± 1
903 ± 12 ± 15 ± 24 ± 15 ± 12 ± 15 ± 1
1203 ± 12 ± 13 ± 13 ± 14 ± 12 ± 15 ± 1
1504 ± 12 ± 14 ± 25 ± 23 ± 14 ± 15 ± 1
1803 ± 12 ± 15 ± 23 ± 14 ± 2
2103 ± 14 ± 28 ± 33 ± 15 ± 2
2404 ± 16 ± 210 ± 34 ± 17 ± 2
2704 ± 15 ± 214 ± 36 ± 27 ± 2
3003 ± 111 ± 312 ± 27 ± 27 ± 2
  • Data are means ± SE. Subjects were studied in the morning (0730–1230) and during the night (2100–0200) while awake and asleep (0000–0200). n = 8 for both groups.