TABLE 3

Annualized rates of progression to abnormal glucose tolerance defined by lower FPG thresholds

FPG <5.55 mmol/l, 2hPG <7.8 mmol/l at baseline	Progression to FPG ≥5.55 mmol/l							Progression to 2hPG ≥7.8 mmol/l
FPG <5.55 mmol/l, 2hPG <7.8 mmol/l at baseline		Outcomes (n)	Person-years	Rate/100	95% CI	Outcomes (n)	Person-years	Rate/100	95% CI
Overall	180	2,838	6.12	5.27–7.07	176	3,179	5.53	4.76–6.40
5-year cumulative incidence		29.9					27.9
10-year cumulative incidence		43.3					42.5
Age
≥65 years	37	549	6.74	4.80–9.16	56	507	11.1	8.40–14.20
<65 years	143	2,390	5.98	5.06–7.02	120	2,672	4.49	3.73–5.34
P			0.5				<0.0001
FPG 5.55–6.09 mmol/l, 2hPG 7.8–11.0 mmol/l at baseline	Progression to FPG ≥6.1 mmol/l							Progression to 2hPG ≥11.1 mmol/l
“Impaired” after “normal” at baseline	33	1,484	2.22	1.55–3.07	28	1,539	1.82	1.23–2.58
5-year cumulative incidence		4.4					4.0
10-year cumulative incidence		21.8					17.0
“Impaired” at baseline	126	3,006	4.19	3.50–4.97	96	3,162	3.03	2.47–3.68
5-year cumulative incidence		19.9					13.7
10-year cumulative incidence		33.4					26.6