Effects of starvation and diabetes on PDP activity in rat heart and kidney mitochondria
| Animal treatment | PDP activity (nmol · min−1 · mg protein−1) | ||
|---|---|---|---|
| Heart | Kidney | ||
| Well-fed | 1.22 ± 0.04 | 1.02 ± 0.05 | |
| Starved (48 h) | 1.00 ± 0.06* | 0.68 ± 0.03† | |
| Starved-refed (48 h) | 1.20 ± 0.11 | 1.00 ± 0.05 | |
| Control | 1.54 ± 0.05 | 1.70 ± 0.08 | |
| Diabetic | 1.14 ± 0.04‡ | 1.22 ± 0.08‡ | |
| Insulin-treated diabetic | 1.40 ± 0.01 | 1.45 ± 0.09 | |
Data are means ± SE for tissue samples obtained from 4–6 animals in each group;
* P < 0.05 compared with well-fed group;
† P < 0.01 compared with well-fed group;
‡ P < 0.01 compared with control group.