TABLE 4

Values for muscle variables before and after control or exercise training periods

VariableControl
Exercise
BeforeAfterBeforeAfter
Citrate synthase activity24.0 ± 1.225.1 ± 1.224.1 ± 0.835.1 ± 1.3*
Cytochrome c oxidase activity6.3 ± 0.67.3 ± 0.87.1 ± 0.513.3 ± 0.7*
COX4 mRNA1.00 ± 0.081.02 ± 0.090.92 ± 0.061.54 ± 0.13*
ND4 mRNA0.76 ± 0.060.77 ± 0.060.73 ± 0.041.19 ± 0.09*
PCG-1 mRNA1.66 ± 0.151.49 ± 0.131.48 ± 0.102.29 ± 0.15*
NRF-1 mRNA0.83 ± 0.100.80 ± 0.100.71 ± 0.060.82 ± 0.07*
TFAM mRNA0.91 ± 0.150.99 ± 0.140.81 ± 0.071.50 ± 0.13*
GLUT4 mRNA0.87 ± 0.070.92 ± 0.080.82 ± 0.061.25 ± 0.07*
  • Data are means ± SE. Enzyme activities are given as μmol·min−1·g−1 tissue; mRNA levels, as arbitrary units after normalization to 28S rRNA.

  • *

    * Before-to-after difference within group, P < 0.001 for all variables except NRF-1, which was P < 0.02. None of the changes in the exercise group had a significant interaction with age or sex.