TABLE 3

Renal response to AngII in groups segregated by N/D ratio

ParameterNormal N/D ratio
High N/D ratio
Baseline1 ng · kg−1 · min−13 ng · kg−1 · min−1RecoveryBaseline1 ng · kg−1 · min−13 ng · kg−1 · min−1Recovery
GFR (ml · min−1 · 1.73 m−2)128 ± 46118 ± 41113 ± 29*117 ± 35142 ± 31142 ± 25141 ± 24137 ± 22
ERPF (ml · min−1 · 1.73 m−2)698 ± 124561 ± 90480 ± 101*502 ± 107756 ± 242617 ± 175532 ± 158*616 ± 190
RBF (ml · min−1 · 1.73 m−2)1,250 ± 4541021 ± 334881 ± 291*1,012 ± 3371,166 ± 289990 ± 289829 ± 203*909 ± 243
FF0.18 ± 0.050.21 ± 0.060.24 ± 0.04*0.24 ± 0.060.20 ± 0.050.24 ± 0.040.28 ± 0.06*0.23 ± 0.05
RVR (mmHg · l−1 · min−1)77 ± 13101 ± 19*134 ± 31*110 ± 2964 ± 1689 ± 27119 ± 34*86 ± 24
MAP (mmHg)83 ± 590 ± 8101 ± 10*85 ± 574 ± 983 ± 997 ± 16*81 ± 11
  • Data are means ± SE.

  • *

    * P < 0.05 vs. baseline;

  • P < 0.05 vs. response of normal N/D ratio group;

  • P < 0.05 vs. baseline value of normal N/D ratio group.