TABLE 1

cGMP content in DRGs of control and diabetic rats

In vivo
Ex vivo
cGMP/protein (fmol/mg) ncGMP/protein (fmol/mg) ncGMP/protein (fmol/mg) n
Diabetic rats
  LY333531 treated148.47 ± 9.84*881.16 ± 1.276
  Untreated91.02 ± 6.01789.24 ± 7.25575.73 ± 0.846
  l-arginine treated113.80 ± 3.845
Control rats
  LY333531 treated123.65 ± 4.44776.83 ± 0.596
  Untreated124.72 ± 7.817116.77 ± 3.09576.47 ± 1.076
  l-arginine treated126.69 ± 6.375
  • Data are means ± SE.

  • *

    * P < 0.01,

  • P < 0.05 compared with untreated diabetic rats.