TABLE 1

Comparison of body weight and serum triglyceride levels at Azgp1, D4Mit336, and D17Mit218 loci in KK/Ta × (BALB/c × KK/Ta) F1 male backcross mice

Phenotypic traitsAzgp1 (Chromosome 5)
PD4Mit336 (Chromosome 4)
PD17Mit218 (Chromosome 17)
P
KKKBKKKBKKKB
Body weight (g)
 8 weeks25.7 ± 0.323.9 ± 0.40.000624.4 ± 0.425.5 ± 0.40.0724.1 ± 0.426.0 ± 0.40.0007
 12 weeks28.4 ± 0.427.0 ± 0.40.00727.1 ± 0.428.4 ± 0.40.0127.0 ± 0.428.5 ± 0.40.08
 20 weeks30.8 ± 0.429.6 ± 0.40.0529.5 ± 0.431.2 ± 0.40.00829.6 ± 0.431.1 ± 0.40.02
 28 weeks31.5 ± 0.530.0 ± 0.40.0230.0 ± 0.531.5 ± 0.40.0230.3 ± 0.531.7 ± 0.50.04
Serum triglyceride levels (mg/dl)
 20 weeks79.3 ± 2.372.9 ± 2.00.0571.8 ± 2.380.5 ± 2.40.00972.7 ± 2.378.7 ± 2.30.07
  • Data expressed as means ± SE: KK is homozygous for the KK/Ta alleles, and KB is heterozygous for the KK/Ta and BALB/c alleles. P < 0.05 by Mann-Whitney U test.