TABLE 1

Plasma parameters in mice that received an ICV infusion of NPY or vehicle under basal or hyperinsulinemic conditions

Basal
Hyperinsulinemic
VehicleNPYVehicleNPY
Body weight (g)23.3 ± 1.222.2 ± 1.223.3 ± 1.222.3 ± 1.4
Glucose (mmol/l)7.0 ± 1.46.8 ± 1.87.5 ± 1.27.7 ± 1.2
FFA (mmol/l)0.7 ± 0.20.7 ± 0.30.2 ± 0.10.3 ± 0.1
Glycerol (mmol/l)0.7 ± 0.20.7 ± 0.10.5 ± 0.10.5 ± 0.1
Insulin (ng/ml)0.8 ± 0.31.0 ± 0.63.5 ± 0.93.9 ± 1.1
Glucagon (pmol/l)100.0 ± 12.499.1 ± 22.071.3 ± 14.566.8 ± 22.2
Corticosterone (ng/ml)29.6 ± 5.421.0 ± 9.926.2 ± 7.225.6 ± 17.6*
  • Data are means ± SD for at least five mice per group.

  • *

    * Data based on two mice only and therefore must be considered with caution.