TABLE 1

Characteristics of wild-type and IRKO mice

Wild-typeIRKOP value
Body weight (g)25.9 ± 0.824.6 ± 0.80.31
Organ weights (% of body wt)
    Heart0.49 ± 0.010.49 ± 0.010.67
    Thoracic aorta0.062 ± 0.0080.059 ± 0.070.63
    Pancreas0.59 ± 0.010.59 ± 0.020.86
    Liver4.92 ± 0.224.87 ± 0.130.88
    Spleen0.29 ± 0.030.33 ± 0.010.29
    Lungs0.71 ± 0.050.63 ± 0.040.25
    Kidney0.62 ± 0.030.64 ± 0.010.68
Perigonadal fat (% of body wt)1.66 ± 0.221.83 ± 0.110.54
Plasma triglycerides (mmol/l)1.48 ± 0.21.44 ± 0.20.57
Plasma free fatty acids (mmol/l)0.9 ± 0.11.2 ± 0.20.23
Systolic blood pressure (mmHg)110 ± 3124 ± 40.01
  • Data are means ± SE (n = 8 per group).