TABLE 2

Results of regions of MLS ≥1.18 from the multipoint linkage analysis on chromosome 6

Group	Cytogenetic location	Distance from p-terminal (cM)	Marker genotyped at the peak	MLS	NPL score	Empirical chromosomal P*
Entire group
First set	6q21–q23	128.9	D6S1040	3.51	3.36	0.003
Second set	6q22–q23	137.7	D6S1009	2.71	2.97	0.003
Combined set	6q21–q23	128.9	D6S1040	6.23	4.48	<0.001
Age-at-diagnosis <40 years subgroup
First set	6q21–q23	128.9	D6S1040	1.29	2.00	0.013
Second set	6q15–q21	102.8	D6S1056	1.74	2.26	0.010
Combined set	6q22–q23	137.7	D6S1009	2.47	2.84	0.011
Age-at-diagnosis ≥40 years subgroup
First set	6q21–q23	128.9	D6S1040	2.29	2.73	0.008
Second set	6q22–q23	137.7	D6S1009	1.79	2.43	0.001
Combined set	6q21–q23	128.9	D6S1040	4.33	3.74	<0.001