Results of regions with MLS ≥1.18 from the multipoint linkage analysis on chromosome 1
| Group | Cytogenetic location | Distance from p-terminal (cM) | Marker genotyped at the peak | MLS | NPL score | Empirical chromosomal P* |
|---|---|---|---|---|---|---|
| Entire group | ||||||
| Second set | 1p35–p34 | 45.3 | D1S552 | 1.37 | 2.09 | 0.078 |
| 1q21–q24 | 192.1 | D1S1589 | 1.83 | 2.54 | 0.057 | |
| Combined set | 1q21–q24 | 192.1 | D1S1589 | 1.16 | 2.00 | 0.043 |
| Age-at-diagnosis <40 years subgroup | ||||||
| First set | 1q21–q25 | 192.1 | D1S1589 | 3.26 | 3.39 | 0.001 |
| Second set | 1p36–p34 | 37.1 | GATA29A05 | 4.36 | 4.10 | <0.001 |
| 1p22–p13 | 109.0 | D1S1728 | 3.39 | 3.31 | 0.005 | |
| 1q21–q24 | 192.1 | D1S1589 | 6.06 | 4.84 | <0.001 | |
| Combined set | 1p36–p35 | 29.9 | D1S1597 | 2.17 | 2.55 | 0.028 |
| 1q21–q24 | 192.1 | D1S1589 | 8.91 | 5.70 | <0.001 |
* Results from analysis of 1,000 replicates of the respective sets.