TABLE 2

Associations between SNPs in adiponectin gene and risk of type 2 diabetes

Case subjectsControl subjectsUnadjusted ORMultivariate OR*
SNP-11365C/C357 (55.6)557 (56.0)1.01.0
C/G244 (38.0)379 (38.1)1.00 (0.81–1.23)1.01 (0.81–1.27)
G/G41 (6.4)59 (5.9)1.08 (0.71–1.64)1.02 (0.65–1.59)
SNP-4034A/A292 (45.5)418 (42.0)1.01.0
A/C280 (43.6)439 (44.1)0.92 (0.74–1.13)0.96 (0.76–1.20)
C/C70 (10.9)138 (13.9)0.73 (0.53–1.01)0.70 (0.50–0.99)
SNP-3964A/A440 (68.5)633 (63.6)1.01.0
A/G177 (27.6)331 (33.3)0.78 (0.63–0.97)0.79 (0.62–1.00)
G/G25 (3.9)31 (3.1)1.16 (0.68–2.00)1.20 (0.67–2.13)
SNP + 45T/T518 (80.7)785 (78.9)1.01.0
T/G + G/G124 (19.3)210 (21.1)0.90 (0.70–1.15)0.91 (0.70–1.19)
SNP + 276G/G322 (50.2)523 (52.6)1.01.0
G/T266 (41.4)399 (40.1)1.08 (0.88–1.34)1.16 (0.93–1.45)
T/T54 (8.4)73 (7.3)1.20 (0.82–1.75)1.22 (0.81–1.82)
  • Data are n (%) or OR (95% CI).

  • *

    * Adjusted for age (5-year categories), alcohol consumption (nondrinkers, 0–4.9, 5–10, or >10 g/day), physical activity (quintiles of metabolic equivalent hours/week), smoking (never, past, and current smoker of 1–14, 15–24, and ≥25 cigarettes/day), and BMI (<23, 23–24.9, 25–29.9, 30–34.9, and ≥35 kg/m2).