TABLE 2

Glucose and insulin parameters during OGTT in a subgroup of obese children; a group of age-matched nonobese children is presented for comparison

UCP2 genotypeObese children
Lean children
GGGAAA
n46681538
Male/female22/2428/406/918/30
Age (years)12.1 ± 0.411.7 ± 0.311.6 ± 0.911.1 ± 0.6
BMI (kg/m2)30.0 ± 0.830.1 ± 0.630.2 ± 1.616.6 ± 0.2*
Fasting insulin (pmol/l)117 ± 9106 ± 7107 ± 1557 ± 2*
Fasting glucose (mmol/l)4.4 ± 0.14.3 ± 0.14.4 ± 0.14.4 ± 0.1
Insulin area (×103 pmol/l)76 ± 776 ± 774 ± 1028 ± 2*
Glucose area (mmol/l)744 ± 13737 ± 12724 ± 17700 ± 14
  • Data are means ± SE.

  • *

    * P < 0.001 vs. the whole cohort of 129 obese children.