TABLE 3

Retinopathy (≥3-step change on Early Treatment Diabetic Retinopathy Study scale) and albuminuria (AER >40 mg/24 h) during the first 6 years of the DCCT, by stimulated C-peptide in intensively treated patients

UndetectableMinimalBaseline-onlySustained
Retinopathy6.5 ± 0.73.5 ± 0.51.8 ± 0.91.4 ± 0.6
 Unadjustedabbcc
 Adjustedabbb
Albuminuria4.0 ± 0.52.3 ± 0.41.7 ± 0.90.9 ± 0.5
 Unadjustedabbcc
 Adjustedaababb
  • Data are rates ± SE per 100 participant-years. Rates were compared (horizontally) between stimulated C-peptide groups. For each comparison, rates with different letters were significantly different (P ≤ 0.05), without and with adjustment for multiple tests.